TAVR for All? The Surgical Perspective

Xiling Zhang, Thomas Puehler, Derk Frank, Janarthanan Sathananthan, Stephanie Sellers, David Meier, Marcus Both, Philipp Blanke, Hatim Seoudy, Mohammed Saad, Oliver J. Müller, Lars Sondergaard, Georg Lutter*

*Corresponding author for this work

Research output: Contribution to journalReviewResearchpeer-review

3 Citations (Scopus)
13 Downloads (Pure)

Abstract

In spite of the noninferiority of transcatheter aortic valve replacement (TAVR) in high- and intermediate-risk patients, there are still obstacles that need to be overcome before the procedure is further expanded and clinically integrated. The lack of evidence on the long-term durability of the bioprostheses used for TAVR remains of particular concern. In addition, surgery may be preferred over TAVR in patients with bicuspid aortic valve (BAV) or with concomitant pathologies such as other valve diseases (mitral regurgitation/tricuspid regurgitation), aortopathy, and coronary artery disease. In this review, we discuss and summarize relevant data from clinical trials, current trends, and remaining obstacles, and provide our perspective on the indications for the expansion of TAVR.

Original languageEnglish
Article number223
JournalJournal of Cardiovascular Development and Disease
Volume9
Issue number7
ISSN2308-3425
DOIs
Publication statusPublished - 2022

Bibliographical note

Publisher Copyright:
© 2022 by the authors.

Keywords

  • aortic valve stenosis
  • high risk
  • intermediate risk
  • low risk
  • surgical aortic valve replacement (SAVR)
  • transcatheter aortic valve implantation (TAVI)
  • transcatheter aortic valve replacement (TAVR)

Cite this