The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients

Lasse Bremholm; Mads Hornum; Ulrik B Andersen; Bolette Hartmann; Jens Juul Holst; Palle Bekker Jeppesen

doi:10.1016/j.regpep.2011.03.003

The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients

Lasse Bremholm, Mads Hornum, Ulrik B Andersen, Bolette Hartmann, Jens Juul Holst, Palle Bekker Jeppesen

Research output: Contribution to journal › Journal article › Research › peer-review

85 Citations (Scopus)

Abstract

Exogenous Glucagon-Like Peptide-2 (GLP-2) treatment improves intestinal wet weight absorption in short bowel syndrome (SBS) patients. In healthy subjects, administration of GLP-2 increases small intestinal blood flow. The aim of the study was to evaluate the effect of GLP-2 on mesenteric blood flow and dynamic changes in cardiac parameters in SBS patients with jejunostomy and varying length of remnant small intestine.

Original language	English
Journal	Regulatory Peptides
Volume	168
Issue number	1-3
Pages (from-to)	32-8
Number of pages	7
ISSN	0167-0115
DOIs	https://doi.org/10.1016/j.regpep.2011.03.003
Publication status	Published - 2011

Keywords

Adult
Aged
Blood Pressure
Cardiac Output
Female
Glucagon-Like Peptide 2
Heart Rate
Humans
Male
Mesenteric Arteries
Middle Aged
Regional Blood Flow
Short Bowel Syndrome
Young Adult

Access to Document

10.1016/j.regpep.2011.03.003

Cite this

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title = "The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients",

abstract = "Exogenous Glucagon-Like Peptide-2 (GLP-2) treatment improves intestinal wet weight absorption in short bowel syndrome (SBS) patients. In healthy subjects, administration of GLP-2 increases small intestinal blood flow. The aim of the study was to evaluate the effect of GLP-2 on mesenteric blood flow and dynamic changes in cardiac parameters in SBS patients with jejunostomy and varying length of remnant small intestine.",

keywords = "Adult, Aged, Blood Pressure, Cardiac Output, Female, Glucagon-Like Peptide 2, Heart Rate, Humans, Male, Mesenteric Arteries, Middle Aged, Regional Blood Flow, Short Bowel Syndrome, Young Adult",

author = "Lasse Bremholm and Mads Hornum and Andersen, {Ulrik B} and Bolette Hartmann and Holst, {Jens Juul} and Jeppesen, {Palle Bekker}",

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T1 - The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients

AU - Bremholm, Lasse

AU - Hornum, Mads

AU - Andersen, Ulrik B

AU - Hartmann, Bolette

AU - Holst, Jens Juul

AU - Jeppesen, Palle Bekker

PY - 2011

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AB - Exogenous Glucagon-Like Peptide-2 (GLP-2) treatment improves intestinal wet weight absorption in short bowel syndrome (SBS) patients. In healthy subjects, administration of GLP-2 increases small intestinal blood flow. The aim of the study was to evaluate the effect of GLP-2 on mesenteric blood flow and dynamic changes in cardiac parameters in SBS patients with jejunostomy and varying length of remnant small intestine.

KW - Adult

KW - Aged

KW - Blood Pressure

KW - Cardiac Output

KW - Female

KW - Glucagon-Like Peptide 2

KW - Heart Rate

KW - Humans

KW - Male

KW - Mesenteric Arteries

KW - Middle Aged

KW - Regional Blood Flow

KW - Short Bowel Syndrome

KW - Young Adult

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DO - 10.1016/j.regpep.2011.03.003

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JO - Regulatory Peptides

JF - Regulatory Peptides

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