TY - JOUR
T1 - The genetic association of variants in CD6, TNFRSF1A and IRF8 to multiple sclerosis: a multicenter case-control study
AU - Oturai, Annette
AU - Søndergaard, Helle Bach
AU - Sørensen, Per Soelberg
AU - International Multiple Sclerosis Genetics Consortium
PY - 2011
Y1 - 2011
N2 - In the recently published meta-analysis of multiple sclerosis genome-wide association studies De Jager et al. identified three single nucleotide polymorphisms associated to MS: rs17824933 (CD6), rs1800693 (TNFRSF1A) and rs17445836 (61.5 kb from IRF8). To refine our understanding of these associations we sought to replicate these findings in a large more extensive independent sample set of 11 populations of European origin.
AB - In the recently published meta-analysis of multiple sclerosis genome-wide association studies De Jager et al. identified three single nucleotide polymorphisms associated to MS: rs17824933 (CD6), rs1800693 (TNFRSF1A) and rs17445836 (61.5 kb from IRF8). To refine our understanding of these associations we sought to replicate these findings in a large more extensive independent sample set of 11 populations of European origin.
U2 - 10.1371/journal.pone.0018813
DO - 10.1371/journal.pone.0018813
M3 - Journal article
SN - 1932-6203
VL - 6
SP - e18813
JO - P L o S One
JF - P L o S One
IS - 4
ER -