The OMERACT Knee Inflammation MRI Scoring System: Validation of quantitative methodologies and tri-compartmental overlays in osteoarthritis

Walter P. Maksymowych; Andrew McReynolds; Susanne J. Pedersen; Ulrich Weber; Joel Paschke; Stephanie Wichuk; Jacob L. Jaremko; Robert G. Lambert

doi:10.1016/j.semarthrit.2021.05.014

The OMERACT Knee Inflammation MRI Scoring System: Validation of quantitative methodologies and tri-compartmental overlays in osteoarthritis

Walter P. Maksymowych^*, Andrew McReynolds, Susanne J. Pedersen, Ulrich Weber, Joel Paschke, Stephanie Wichuk, Jacob L. Jaremko, Robert G. Lambert

^*Corresponding author for this work

Department of Clinical Medicine

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Abstract

Objective: To validate a revised version of the KIMRISS method for quantification of BML and synovitis-effusion in the knee by comparison with an established method, MOAKS. Methods: Novel calibration tools were developed for both methods. We compared reliability for status and change scores of BML and synovitis-effusion on baseline and one-year MRI scans. Results: Significant increase in both BML and synovitis-effusion was evident using KIMRISS but only for synovitis-effusion using MOAKS. Pre-specified targets for acceptable reliability (≥0.80 and ≥0.70 for status and change scores, respectively) were achieved more frequently for KIMRISS for both BML and synovitis. Conclusion: Per OFISA criteria, KIMRISS should progress to assessment of discrimination.

Original language	English
Journal	Seminars in Arthritis and Rheumatism
Volume	51
Issue number	4
Pages (from-to)	925-928
ISSN	0049-0172
DOIs	https://doi.org/10.1016/j.semarthrit.2021.05.014
Publication status	Published - 2021

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Inc.

Keywords

Bone marrow lesions
Knee inflammation MRI scoring system (KIMRISS)
MRI
OMERACT
Osteoarthritis

Access to Document

10.1016/j.semarthrit.2021.05.014

Cite this

Maksymowych, W. P., McReynolds, A., Pedersen, S. J., Weber, U., Paschke, J., Wichuk, S., Jaremko, J. L., & Lambert, R. G. (2021). The OMERACT Knee Inflammation MRI Scoring System: Validation of quantitative methodologies and tri-compartmental overlays in osteoarthritis. Seminars in Arthritis and Rheumatism, 51(4), 925-928. https://doi.org/10.1016/j.semarthrit.2021.05.014

The OMERACT Knee Inflammation MRI Scoring System : Validation of quantitative methodologies and tri-compartmental overlays in osteoarthritis. / Maksymowych, Walter P.; McReynolds, Andrew; Pedersen, Susanne J.; Weber, Ulrich; Paschke, Joel; Wichuk, Stephanie; Jaremko, Jacob L.; Lambert, Robert G.

In: Seminars in Arthritis and Rheumatism, Vol. 51, No. 4, 2021, p. 925-928.

Research output: Contribution to journal › Journal article › Research › peer-review

Maksymowych, Walter P. ; McReynolds, Andrew ; Pedersen, Susanne J. ; Weber, Ulrich ; Paschke, Joel ; Wichuk, Stephanie ; Jaremko, Jacob L. ; Lambert, Robert G. / The OMERACT Knee Inflammation MRI Scoring System : Validation of quantitative methodologies and tri-compartmental overlays in osteoarthritis. In: Seminars in Arthritis and Rheumatism. 2021 ; Vol. 51, No. 4. pp. 925-928.

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title = "The OMERACT Knee Inflammation MRI Scoring System: Validation of quantitative methodologies and tri-compartmental overlays in osteoarthritis",

abstract = "Objective: To validate a revised version of the KIMRISS method for quantification of BML and synovitis-effusion in the knee by comparison with an established method, MOAKS. Methods: Novel calibration tools were developed for both methods. We compared reliability for status and change scores of BML and synovitis-effusion on baseline and one-year MRI scans. Results: Significant increase in both BML and synovitis-effusion was evident using KIMRISS but only for synovitis-effusion using MOAKS. Pre-specified targets for acceptable reliability (≥0.80 and ≥0.70 for status and change scores, respectively) were achieved more frequently for KIMRISS for both BML and synovitis. Conclusion: Per OFISA criteria, KIMRISS should progress to assessment of discrimination.",

keywords = "Bone marrow lesions, Knee inflammation MRI scoring system (KIMRISS), MRI, OMERACT, Osteoarthritis",

author = "Maksymowych, {Walter P.} and Andrew McReynolds and Pedersen, {Susanne J.} and Ulrich Weber and Joel Paschke and Stephanie Wichuk and Jaremko, {Jacob L.} and Lambert, {Robert G.}",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier Inc.",

year = "2021",

doi = "10.1016/j.semarthrit.2021.05.014",

language = "English",

volume = "51",

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T1 - The OMERACT Knee Inflammation MRI Scoring System

T2 - Validation of quantitative methodologies and tri-compartmental overlays in osteoarthritis

AU - Maksymowych, Walter P.

AU - McReynolds, Andrew

AU - Pedersen, Susanne J.

AU - Weber, Ulrich

AU - Paschke, Joel

AU - Wichuk, Stephanie

AU - Jaremko, Jacob L.

AU - Lambert, Robert G.

PY - 2021

Y1 - 2021

N2 - Objective: To validate a revised version of the KIMRISS method for quantification of BML and synovitis-effusion in the knee by comparison with an established method, MOAKS. Methods: Novel calibration tools were developed for both methods. We compared reliability for status and change scores of BML and synovitis-effusion on baseline and one-year MRI scans. Results: Significant increase in both BML and synovitis-effusion was evident using KIMRISS but only for synovitis-effusion using MOAKS. Pre-specified targets for acceptable reliability (≥0.80 and ≥0.70 for status and change scores, respectively) were achieved more frequently for KIMRISS for both BML and synovitis. Conclusion: Per OFISA criteria, KIMRISS should progress to assessment of discrimination.

AB - Objective: To validate a revised version of the KIMRISS method for quantification of BML and synovitis-effusion in the knee by comparison with an established method, MOAKS. Methods: Novel calibration tools were developed for both methods. We compared reliability for status and change scores of BML and synovitis-effusion on baseline and one-year MRI scans. Results: Significant increase in both BML and synovitis-effusion was evident using KIMRISS but only for synovitis-effusion using MOAKS. Pre-specified targets for acceptable reliability (≥0.80 and ≥0.70 for status and change scores, respectively) were achieved more frequently for KIMRISS for both BML and synovitis. Conclusion: Per OFISA criteria, KIMRISS should progress to assessment of discrimination.

KW - Bone marrow lesions

KW - Knee inflammation MRI scoring system (KIMRISS)

KW - MRI

KW - OMERACT

KW - Osteoarthritis

U2 - 10.1016/j.semarthrit.2021.05.014

DO - 10.1016/j.semarthrit.2021.05.014

M3 - Journal article

C2 - 34167825

AN - SCOPUS:85108512452

VL - 51

SP - 925

EP - 928

JO - Seminars in Arthritis and Rheumatism

JF - Seminars in Arthritis and Rheumatism

SN - 0049-0172

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ER -