The OMERACT MRI in enthesitis initiative: Definitions of key pathologies, suggested MRI sequences, and a novel heel enthesitis scoring system

Ashish J. Mathew, Simon Krabbe, Iris Eshed, Frédérique Gandjbakhch, Paul Bird, Susanne J. Pedersen, Maria S. Stoenoiu, Violaine Foltz, Daniel Glinatsi, Robert G. Lambert, Kay Geert A. Hermann, Walter P. Maksymowych, Ida K. Haugen, Jacob L. Jaremko, René P. Poggenborg, Joel Paschke, Jean Denis Laredo, Philippe Carron, Philip G. Conaghan, Mikkel Østergaard*

*Corresponding author for this work

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Abstract

Objective. To develop and validate an enthesitis magnetic resonance imaging (MRI) scoring system for spondyloarthritis/psoriatic arthritis, using the heel as model. Methods. Consensus definitions of key pathologies and 3 heel enthesitis multireader scoring exercises were done, separated by discussion, training, and calibration. Results. Definitions for bone and soft tissue pathologies were agreed. In the final exercise, median pairwise single-measures intraclass correlation coefficients (ICC; patient-level) for entheseal inflammation status/change scores were 0.83/0.82 for all readers. For radiologists and selected rheumatologists, ICC were 0.91/0.84 and quadratic-weighted κ (lesion-level) 0.57-0.91/0.45-0.81. Conclusion. The proposed definitions and Heel Enthesitis Scoring System (HEMRIS) are reliable among trained readers and promising for clinical trials.

Original languageEnglish
JournalJournal of Rheumatology
Volume46
Issue number9
Pages (from-to)1232-1238
Number of pages7
ISSN0315-162X
DOIs
Publication statusPublished - 2019

Keywords

  • Enthesopathy
  • Magnetic resonance imaging
  • Omeract
  • Psoriatic arthritis
  • Spondyloarthropathy

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