The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors

K Hoestgaard-Jensen, R M O'Connor, Nils Ole Dalby, C Simonsen, B C Finger, A Golubeva, H Hammer, M L Bergmann, U Kristiansen, P Krogsgaard-Larsen, H Bräuner-Osborne, B Ebert, B Frølund, J F Cryan, A A Jensen

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16 Citations (Scopus)

Abstract

Explorations into the heterogeneous population of native GABA type A receptors (GABAA Rs) and the physiological functions governed by the multiple GABAA R subtypes have for decades been hampered by the lack of subtype-selective ligands.
Original languageEnglish
JournalBritish Journal of Pharmacology
Volume170
Issue number4
Pages (from-to)919-32
Number of pages14
ISSN0007-1188
DOIs
Publication statusPublished - Oct 2013

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