The potential of antimicrobials to induce thrombocytopenia in critically ill patients: data from a randomized controlled trial

Maria Egede Johansen; Jens Ulrik Stæhr Jensen; Morten Heiberg Bestle; Lars Hein; Anne Øberg Lauritsen; Hamid Tousi; Kim Michael Larsen; Jesper Løken; Thomas Mohr; Katrin Thormar; Pär I Johansson; Alessandro Cozzi-Lepri; Jens D Lundgren

doi:10.1371/journal.pone.0081477

The potential of antimicrobials to induce thrombocytopenia in critically ill patients: data from a randomized controlled trial

Maria Egede Johansen, Jens Ulrik Stæhr Jensen, Morten Heiberg Bestle, Lars Hein, Anne Øberg Lauritsen, Hamid Tousi, Kim Michael Larsen, Jesper Løken, Thomas Mohr, Katrin Thormar, Pär I Johansson, Alessandro Cozzi-Lepri, Jens D Lundgren

Department of Clinical Medicine

Research output: Contribution to journal › Journal article › Research

18 Citations (Scopus)

Abstract

Antimicrobial-induced thrombocytopenia is frequently described in the literature among critically ill patients. Several antimicrobials have been implicated, although experimental evidence to demonstrate causality is limited. We report, using a randomized trial, the potential of antimicrobials to induce thrombocytopenia.

Original language	English
Journal	PloS one
Volume	8
Issue number	11
Pages (from-to)	e81477
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0081477
Publication status	Published - 2013

Access to Document

10.1371/journal.pone.0081477

Cite this

Johansen, M. E., Jensen, J. U. S., Bestle, M. H., Hein, L., Lauritsen, A. Ø., Tousi, H., Larsen, K. M., Løken, J., Mohr, T., Thormar, K., Johansson, P. I., Cozzi-Lepri, A., & Lundgren, J. D. (2013). The potential of antimicrobials to induce thrombocytopenia in critically ill patients: data from a randomized controlled trial. PloS one, 8(11), e81477. https://doi.org/10.1371/journal.pone.0081477

Johansen, ME, Jensen, JUS , Bestle, MH, Hein, L, Lauritsen, AØ, Tousi, H, Larsen, KM, Løken, J, Mohr, T, Thormar, K, Johansson, PI, Cozzi-Lepri, A & Lundgren, JD 2013, 'The potential of antimicrobials to induce thrombocytopenia in critically ill patients: data from a randomized controlled trial', PloS one, vol. 8, no. 11, pp. e81477. https://doi.org/10.1371/journal.pone.0081477

@article{ed1dcd4666c54179b0c2e5087ad855c5,

title = "The potential of antimicrobials to induce thrombocytopenia in critically ill patients: data from a randomized controlled trial",

abstract = "Antimicrobial-induced thrombocytopenia is frequently described in the literature among critically ill patients. Several antimicrobials have been implicated, although experimental evidence to demonstrate causality is limited. We report, using a randomized trial, the potential of antimicrobials to induce thrombocytopenia.",

author = "Johansen, {Maria Egede} and Jensen, {Jens Ulrik St{\ae}hr} and Bestle, {Morten Heiberg} and Lars Hein and Lauritsen, {Anne {\O}berg} and Hamid Tousi and Larsen, {Kim Michael} and Jesper L{\o}ken and Thomas Mohr and Katrin Thormar and Johansson, {P{\"a}r I} and Alessandro Cozzi-Lepri and Lundgren, {Jens D}",

year = "2013",

doi = "10.1371/journal.pone.0081477",

language = "English",

volume = "8",

pages = "e81477",

journal = "PloS one",

issn = "1932-6203",

publisher = "Public Library of Science",

number = "11",

}

TY - JOUR

T1 - The potential of antimicrobials to induce thrombocytopenia in critically ill patients

T2 - data from a randomized controlled trial

AU - Johansen, Maria Egede

AU - Jensen, Jens Ulrik Stæhr

AU - Bestle, Morten Heiberg

AU - Hein, Lars

AU - Lauritsen, Anne Øberg

AU - Tousi, Hamid

AU - Larsen, Kim Michael

AU - Løken, Jesper

AU - Mohr, Thomas

AU - Thormar, Katrin

AU - Johansson, Pär I

AU - Cozzi-Lepri, Alessandro

AU - Lundgren, Jens D

PY - 2013

Y1 - 2013

N2 - Antimicrobial-induced thrombocytopenia is frequently described in the literature among critically ill patients. Several antimicrobials have been implicated, although experimental evidence to demonstrate causality is limited. We report, using a randomized trial, the potential of antimicrobials to induce thrombocytopenia.

AB - Antimicrobial-induced thrombocytopenia is frequently described in the literature among critically ill patients. Several antimicrobials have been implicated, although experimental evidence to demonstrate causality is limited. We report, using a randomized trial, the potential of antimicrobials to induce thrombocytopenia.

U2 - 10.1371/journal.pone.0081477

DO - 10.1371/journal.pone.0081477

M3 - Journal article

C2 - 24312305

SN - 1932-6203

VL - 8

SP - e81477

JO - PloS one

JF - PloS one

IS - 11

ER -