The significance of HIV to bone mineral density

Maria Wessman, Nina Weis, Terese L. Katzenstein, Anne Mette Lebech, Kristina Thorsteinsson, Ann Brit Eg Hansen, Jens Erik Beck Jensen

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Abstract

The life expectancy in well-treated HIV-infected persons approaches that of the general population, but HIV-infected persons have a greater incidence of fractures and osteoporosis. A decrease in bone mineral density is observed primarily during the first 1-2 years of antiretroviral therapy. Dual X-ray absorptiometry scan should be considered in HIV-infected men ≥ 50 years and postmenopausal women. In case of osteoporosis, bisphosphonate treatment should follow guidelines for the general population. Future research should focus on pathogenesis and prevention of bone density loss in HIV.

Original languageEnglish
JournalUgeskrift for Laeger
Volume179
Issue number36
ISSN0041-5782
Publication statusPublished - 4 Sep 2017

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