The viability and spatial distribution of osteocytes in the human labyrinthine capsule: a quantitative study using vector-based stereology

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    Abstract

    Bone remodeling is highly inhibited around the labyrinthine space, most likely by the action of the anti-resorptive cytokine osteoprotegerin (OPG). Inner ear OPG may enter the bony otic capsule through the lacuno-canalicular porosity (LCP). The aim of the study was to investigate the patency of this extracellular signaling pathway by exploring the viability, age dependency and spatial distribution of capsular osteocytes.
    Original languageEnglish
    JournalHearing Research
    Volume270
    Issue number1-2
    Pages (from-to)65-70
    Number of pages6
    ISSN0378-5955
    DOIs
    Publication statusPublished - 1 Dec 2010

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