Theoretical models of phospholipid phase transitions

O. G. Mouritsen

doi:10.1016/0009-3084(91)90075-M

Theoretical models of phospholipid phase transitions

O. G. Mouritsen^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › Research › peer-review

151 Citations (Scopus)

Abstract

A brief review is given of the theoretical models and calculational methods used to study the main phase transition in phospholipid membranes with particular emphasis on recent progress. The models are discussed in terms of the mechanical variables and the various interactions which are necessary to describe the phase transition. Theoretical results are presented for the transitional properties and how the phase equilibria are affected by "impurities" such as cholesterol, proteins and anaesthetics.

Original language	English
Journal	Chemistry and Physics of Lipids
Volume	57
Issue number	2-3
Pages (from-to)	179-194
Number of pages	16
ISSN	0009-3084
DOIs	https://doi.org/10.1016/0009-3084(91)90075-M
Publication status	Published - 1991
Externally published	Yes

Keywords

anaeshtetics
bilayer
fluctuations
lipid-cholesterol interaction
lipid-protein interaction
phase transition
phospholipid

Access to Document

10.1016/0009-3084(91)90075-M

Cite this

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title = "Theoretical models of phospholipid phase transitions",

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AU - Mouritsen, O. G.

PY - 1991

Y1 - 1991

N2 - A brief review is given of the theoretical models and calculational methods used to study the main phase transition in phospholipid membranes with particular emphasis on recent progress. The models are discussed in terms of the mechanical variables and the various interactions which are necessary to describe the phase transition. Theoretical results are presented for the transitional properties and how the phase equilibria are affected by "impurities" such as cholesterol, proteins and anaesthetics.

AB - A brief review is given of the theoretical models and calculational methods used to study the main phase transition in phospholipid membranes with particular emphasis on recent progress. The models are discussed in terms of the mechanical variables and the various interactions which are necessary to describe the phase transition. Theoretical results are presented for the transitional properties and how the phase equilibria are affected by "impurities" such as cholesterol, proteins and anaesthetics.

KW - anaeshtetics

KW - bilayer

KW - fluctuations

KW - lipid-cholesterol interaction

KW - lipid-protein interaction

KW - phase transition

KW - phospholipid

U2 - 10.1016/0009-3084(91)90075-M

DO - 10.1016/0009-3084(91)90075-M

M3 - Journal article

C2 - 2054903

AN - SCOPUS:0025978450

VL - 57

SP - 179

EP - 194

JO - Chemistry and Physics of Lipids

JF - Chemistry and Physics of Lipids

SN - 0009-3084

IS - 2-3

ER -