@article{0dcf79d4681349588f9afc9c983c4508,
title = "Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis",
abstract = "A Topoisomerase 1 (Top1) poison is frequently included in the treatment regimens for metastatic colorectal cancer (mCRC). However, no predictive biomarkers for Top1 poisons are available. We here report a study on the TOP1 gene copy number in CRC patients and its association with patient prognosis and tumor cell proliferation.",
keywords = "Former LIFE faculty, Colorectal cancer, Prognosis, FISH, Topoisomerase 1, Gene copy number, Biomarker",
author = "R{\o}mer, {Maria Unni Koefoed} and Nyg{\aa}rd, {Sune Boris} and Christensen, {Ib Jarle} and Nielsen, {Signe Lykke} and Nielsen, {Kirsten Vang} and Sven M{\"u}ller and Smith, {David Hersi} and Ben Vainer and Nielsen, {Hans J{\o}rgen} and Nils Br{\"u}nner",
note = "Copyright {\textcopyright} 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.",
year = "2013",
doi = "10.1016/j.molonc.2012.09.001",
language = "English",
volume = "7",
pages = "101--111",
journal = "Molecular Oncology",
issn = "1574-7891",
publisher = "Elsevier",
number = "1",
}