Abstract
Polymorphism and other solid-state phenomena can have effects on many physicochemical properties of pharmaceuticals. In this commentary, some aspects of solid-state pharmaceutics that are important to dissolution testing are highlighted. Examples of how solid-state analysis can be used to aid interpretation of dissolution results are also reviewed. We suggest the term physico-relevant dissolution testing to describe the combination of dissolution testing with solid-state analysis.
Original language | English |
---|---|
Journal | Dissolution Technologies |
Volume | 16 |
Issue number | 2 |
Pages (from-to) | 47-54 |
Number of pages | 8 |
ISSN | 1521-298X |
DOIs |
|
Publication status | Published - May 2009 |