Transcatheter Mitral Valve Repair or Replacement: Competitive or Complementary?

Zhang Xiling; Thomas Puehler; Lars Sondergaard; Derk Frank; Hatim Seoudy; Baland Mohammad; Oliver J. Müller; Stephanie Sellers; David Meier; Janarthanan Sathananthan; Georg Lutter

doi:10.3390/jcm11123377

Transcatheter Mitral Valve Repair or Replacement: Competitive or Complementary?

Zhang Xiling, Thomas Puehler, Lars Sondergaard, Derk Frank, Hatim Seoudy, Baland Mohammad, Oliver J. Müller, Stephanie Sellers, David Meier, Janarthanan Sathananthan, Georg Lutter^*

^*Corresponding author for this work

Research output: Contribution to journal › Review › Research › peer-review

5 Citations (Scopus)

10 Downloads (Pure)

Abstract

Over the last two decades, transcatheter devices have been developed to repair or replace diseased mitral valves (MV). Transcatheter mitral valve repair (TMVr) devices have been proven to be efficient and safe, but many anatomical structures are not compatible with these technologies. The most significant advantage of transcatheter mitral valve replacement (TMVR) over transcatheter repair is the greater and more reliable reduction in mitral regurgitation. However, there are also potential disadvantages. This review introduces the newest TMVr and TMVR devices and presents clinical trial data to identify current challenges and directions for future research.

Original language	English
Article number	3377
Journal	Journal of Clinical Medicine
Volume	11
Issue number	12
ISSN	2077-0383
DOIs	https://doi.org/10.3390/jcm11123377
Publication status	Published - 2022

Bibliographical note

Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.

Keywords

access
approach
endovascular
mitral insufficiency
mitral regurgitation
percutaneous
transcatheter mitral valve repair
transcatheter mitral valve replacement
transcatheter technology
transluminal

Access to Document

10.3390/jcm11123377Licence: CC BY

FulltextFinal published version, 1.99 MBLicence: CC BY

Cite this

Transcatheter Mitral Valve Repair or Replacement : Competitive or Complementary? / Xiling, Zhang; Puehler, Thomas; Sondergaard, Lars; Frank, Derk; Seoudy, Hatim; Mohammad, Baland; Müller, Oliver J.; Sellers, Stephanie; Meier, David; Sathananthan, Janarthanan; Lutter, Georg.

In: Journal of Clinical Medicine, Vol. 11, No. 12, 3377, 2022.

Research output: Contribution to journal › Review › Research › peer-review

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title = "Transcatheter Mitral Valve Repair or Replacement: Competitive or Complementary?",

abstract = "Over the last two decades, transcatheter devices have been developed to repair or replace diseased mitral valves (MV). Transcatheter mitral valve repair (TMVr) devices have been proven to be efficient and safe, but many anatomical structures are not compatible with these technologies. The most significant advantage of transcatheter mitral valve replacement (TMVR) over transcatheter repair is the greater and more reliable reduction in mitral regurgitation. However, there are also potential disadvantages. This review introduces the newest TMVr and TMVR devices and presents clinical trial data to identify current challenges and directions for future research.",

keywords = "access, approach, endovascular, mitral insufficiency, mitral regurgitation, percutaneous, transcatheter mitral valve repair, transcatheter mitral valve replacement, transcatheter technology, transluminal",

author = "Zhang Xiling and Thomas Puehler and Lars Sondergaard and Derk Frank and Hatim Seoudy and Baland Mohammad and M{\"u}ller, {Oliver J.} and Stephanie Sellers and David Meier and Janarthanan Sathananthan and Georg Lutter",

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AU - Puehler, Thomas

AU - Sondergaard, Lars

AU - Frank, Derk

AU - Seoudy, Hatim

AU - Mohammad, Baland

AU - Müller, Oliver J.

AU - Sellers, Stephanie

AU - Meier, David

AU - Sathananthan, Janarthanan

AU - Lutter, Georg

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AB - Over the last two decades, transcatheter devices have been developed to repair or replace diseased mitral valves (MV). Transcatheter mitral valve repair (TMVr) devices have been proven to be efficient and safe, but many anatomical structures are not compatible with these technologies. The most significant advantage of transcatheter mitral valve replacement (TMVR) over transcatheter repair is the greater and more reliable reduction in mitral regurgitation. However, there are also potential disadvantages. This review introduces the newest TMVr and TMVR devices and presents clinical trial data to identify current challenges and directions for future research.

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KW - transcatheter mitral valve replacement

KW - transcatheter technology

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