Transcatheter mitral valve replacement: Current evidence and concepts

Ozan M. Demir, Mhairi Bolland, Jonathan Curio, Lars Søndergaard, Josep Rodés-Cabau, Simon Redwood, Bernard Prendergast, Antonio Colombo, Mei Chau, Azeem Latib*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

9 Citations (Scopus)
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Abstract

Over the past decade, several transcatheter devices have been developed to address the treatment of severe mitral regurgitation (MR) in patients at high surgical risk, mainly aimed at repairing the native mitral valve (MV). MV repair devices have recently been shown to have high efficacy and safety. However, to replicate promising trial results, specific anatomical and pathophysiological criteria have to be met and operators need a high level of experience. As yet, the longer-term durability of transcatheter MV repair remains unknown. Transcatheter MV replacement (TMVR) might be a treatment option able to target various anatomies, reliably abolish MR, and foster ease of use with a standardised implantation protocol. This review presents upcoming TMVR devices and available data and discusses how TMVR might further advance the field of transcatheter treatment of MR.

Original languageEnglish
Article number07
JournalInterventional Cardiology Review
Volume16
ISSN1756-1477
DOIs
Publication statusPublished - 2021

Bibliographical note

Funding Information:
Disclosure: JRC receives institutional research grants from and is a consultant for Edwards Lifesciences, Medtronic and Abbott. AL is a consultant for Edwards Lifesciences, Medtronic and Abbott. All other authors have no conflicts of interest to declare. Received: 21 August 2020 Accepted: 4 January 2021 Citation: Interventional Cardiology Review 2021;16:e07. DOI: https://doi.org/10.15420/icr.2020.25 Correspondence: Azeem Latib, Department of Cardiology, Montefiore Medical Center, 111 East 210th St, Bronx, New York 10467–2401, US. E: [email protected] Open Access: This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.

Publisher Copyright:
© 2021 Radcliffe Group Ltd. All rights reserved.

Keywords

  • Heart failure
  • Mitral regurgitation
  • Percutaneous mitral valve replacement
  • Transcatheter mitral valve repair
  • Transcatheter mitral valve replacement

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