Tuning wasp toxin structure for nicotinic receptor antagonism: cyclohexylalanine-containing analogues as potent and voltage-dependent blockers

Christian A Olsen; Ian R Mellor; Petrine Wellendorph; Peter N R Usherwood; Matthias Witt; Henrik Franzyk; Jerzy W Jaroszewski

doi:10.1002/cmdc.200500067

Tuning wasp toxin structure for nicotinic receptor antagonism: cyclohexylalanine-containing analogues as potent and voltage-dependent blockers

Christian A Olsen, Ian R Mellor, Petrine Wellendorph, Peter N R Usherwood, Matthias Witt, Henrik Franzyk, Jerzy W Jaroszewski

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Original language	English
Journal	ChemMedChem
Volume	1
Issue number	3
Pages (from-to)	303-5
Number of pages	3
ISSN	1860-7179
DOIs	https://doi.org/10.1002/cmdc.200500067
Publication status	Published - 2006

Keywords

Humans
Ion Channel Gating
Nicotinic Antagonists
Phenylalanine
Polyamines
Receptors, Nicotinic
Wasp Venoms

Access to Document

10.1002/cmdc.200500067

Cite this

Tuning wasp toxin structure for nicotinic receptor antagonism : cyclohexylalanine-containing analogues as potent and voltage-dependent blockers. / Olsen, Christian A; Mellor, Ian R; Wellendorph, Petrine; Usherwood, Peter N R; Witt, Matthias; Franzyk, Henrik; Jaroszewski, Jerzy W.

In: ChemMedChem, Vol. 1, No. 3, 2006, p. 303-5.

Research output: Contribution to journal › Journal article › Research › peer-review

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keywords = "Humans, Ion Channel Gating, Nicotinic Antagonists, Phenylalanine, Polyamines, Receptors, Nicotinic, Wasp Venoms",

author = "Olsen, {Christian A} and Mellor, {Ian R} and Petrine Wellendorph and Usherwood, {Peter N R} and Matthias Witt and Henrik Franzyk and Jaroszewski, {Jerzy W}",

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AU - Mellor, Ian R

AU - Wellendorph, Petrine

AU - Usherwood, Peter N R

AU - Witt, Matthias

AU - Franzyk, Henrik

AU - Jaroszewski, Jerzy W

PY - 2006

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KW - Ion Channel Gating

KW - Nicotinic Antagonists

KW - Phenylalanine

KW - Polyamines

KW - Receptors, Nicotinic

KW - Wasp Venoms

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DO - 10.1002/cmdc.200500067

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