Visualizing biofilm by targeting eDNA with long wavelength probe CDr15

Haw Young Kwon; Jun Young Kim; Xiao Liu; Jung Yeol Lee; Joey Kuok Hoong Yam; Louise Dahl Hultqvist; Wang Xu; Morten Rybtke; Tim Tolker-Nielsen; Wooseok Heo; Jong Jin Kim; Nam Young Kang; Taiha Joo; Liang Yang; Sung Jin Park; Michael Givskov; Young Tae Chang

doi:10.1039/c9bm00152b

Visualizing biofilm by targeting eDNA with long wavelength probe CDr15

Haw Young Kwon, Jun Young Kim, Xiao Liu, Jung Yeol Lee, Joey Kuok Hoong Yam, Louise Dahl Hultqvist, Wang Xu, Morten Rybtke, Tim Tolker-Nielsen, Wooseok Heo, Jong Jin Kim, Nam Young Kang, Taiha Joo, Liang Yang, Sung Jin Park^*, Michael Givskov, Young Tae Chang

^*Corresponding author for this work

Bacteriology

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Abstract

Detection of the biofilm of bacteria would be a counter strategy to detect hidden bacteria in their camouflage. Through unbiased screening of bacteria biofilm, we discovered a long wavelength probe CDr15 with extracellular DNA as the molecular target. CDr15 revealed a real-time geometric distribution of eDNA in a 3D bacterial colony.

Original language	English
Journal	Biomaterials Science
Volume	7
Issue number	9
Pages (from-to)	3594-3598
Number of pages	5
ISSN	2047-4830
DOIs	https://doi.org/10.1039/c9bm00152b
Publication status	Published - 2019

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10.1039/c9bm00152b

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Visualizing biofilm by targeting eDNA with long wavelength probe CDr15. / Kwon, Haw Young; Kim, Jun Young; Liu, Xiao; Lee, Jung Yeol; Yam, Joey Kuok Hoong; Dahl Hultqvist, Louise; Xu, Wang; Rybtke, Morten ; Tolker-Nielsen, Tim; Heo, Wooseok; Kim, Jong Jin; Kang, Nam Young; Joo, Taiha; Yang, Liang; Park, Sung Jin; Givskov, Michael; Chang, Young Tae.

In: Biomaterials Science, Vol. 7, No. 9, 2019, p. 3594-3598.

Research output: Contribution to journal › Journal article › Research › peer-review

Kwon, Haw Young ; Kim, Jun Young ; Liu, Xiao ; Lee, Jung Yeol ; Yam, Joey Kuok Hoong ; Dahl Hultqvist, Louise ; Xu, Wang ; Rybtke, Morten ; Tolker-Nielsen, Tim ; Heo, Wooseok ; Kim, Jong Jin ; Kang, Nam Young ; Joo, Taiha ; Yang, Liang ; Park, Sung Jin ; Givskov, Michael ; Chang, Young Tae. / Visualizing biofilm by targeting eDNA with long wavelength probe CDr15. In: Biomaterials Science. 2019 ; Vol. 7, No. 9. pp. 3594-3598.

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abstract = "Detection of the biofilm of bacteria would be a counter strategy to detect hidden bacteria in their camouflage. Through unbiased screening of bacteria biofilm, we discovered a long wavelength probe CDr15 with extracellular DNA as the molecular target. CDr15 revealed a real-time geometric distribution of eDNA in a 3D bacterial colony.",

author = "Kwon, {Haw Young} and Kim, {Jun Young} and Xiao Liu and Lee, {Jung Yeol} and Yam, {Joey Kuok Hoong} and {Dahl Hultqvist}, Louise and Wang Xu and Morten Rybtke and Tim Tolker-Nielsen and Wooseok Heo and Kim, {Jong Jin} and Kang, {Nam Young} and Taiha Joo and Liang Yang and Park, {Sung Jin} and Michael Givskov and Chang, {Young Tae}",

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AU - Kwon, Haw Young

AU - Kim, Jun Young

AU - Liu, Xiao

AU - Lee, Jung Yeol

AU - Yam, Joey Kuok Hoong

AU - Dahl Hultqvist, Louise

AU - Xu, Wang

AU - Rybtke, Morten

AU - Tolker-Nielsen, Tim

AU - Heo, Wooseok

AU - Kim, Jong Jin

AU - Kang, Nam Young

AU - Joo, Taiha

AU - Yang, Liang

AU - Park, Sung Jin

AU - Givskov, Michael

AU - Chang, Young Tae

PY - 2019

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AB - Detection of the biofilm of bacteria would be a counter strategy to detect hidden bacteria in their camouflage. Through unbiased screening of bacteria biofilm, we discovered a long wavelength probe CDr15 with extracellular DNA as the molecular target. CDr15 revealed a real-time geometric distribution of eDNA in a 3D bacterial colony.

U2 - 10.1039/c9bm00152b

DO - 10.1039/c9bm00152b

M3 - Journal article

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AN - SCOPUS:85071377082

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EP - 3598

JO - Biomaterials Science

JF - Biomaterials Science

SN - 2047-4830

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